What is this

Celiac disease (also known as gluten-intolerance) is a disorder that involves a chronic immunologic reaction to the gluten contained in some cereal grains. This reaction causes destruction of villi, the tiny, fingerlike protrusions lining the small intestine, resulting in malabsorption of nutrients.
Disease symptoms include diarrhoea, abdominal bloating, weight loss, , malnutrition and skin reactions. Diagnosis based on the detection of antibodies is rather accurate. It is worth mentioning that current guidelines like from the “American College of Gastroenterology” indicate that IgA anti-tTG detection remains the first choice marker for diagnosing coeliac disease in patients aged over 2 years old.

Our test

Celiac Test is an immunochromatographic test designed to detect, in human blood and serum, IgA-type antibodies against human tissue transglutaminase (tTG), the main autoantigen recognized by the anti-endomysial antibodies, and antibodies against gliadins. The test uses a combination of:
1) red latex bead-conjugated human anti-IgA antibodies that will bond to the IgAs present in the sample and that will be taken up by the recombinant human tTG located in the membrane (position T1) if the sample contains IgA anti-tTGs, and/or deamidated gliadin peptides (DGP, position T2) if the sample presents anti-gliadin IgAs. 2) blue latex particles conjugated to an antigen recognized by an antibody specific for this antigen bound to the membrane forming the so called test control band.

Celiac Test 75 €